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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

When Is Drinking Out of Control? Spotting the Signs Before It’s Too Late

When Is Drinking Out of Control? Spotting the Signs Before It’s Too Late

When Is Drinking Out of Control? Spotting the Signs Before It’s Too LateBruce Rose
Published on: 15/05/2025

Alcohol can start off as a way to relax, celebrate, or socialise. But over time, that relationship can shift—sometimes subtly, sometimes dramatically. Out of control drinking isn’t always obvious. It can creep into your routines, habits, and mental health without you noticing until real damage has been done.

The Sinclair Method (TSM)
Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method

Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method

Published on: 06/05/2025

Alcohol dependency isn’t about weakness or moral failure. It’s a complex condition involving the brain’s natural reward mechanisms. When we drink alcohol, our brains release endorphins—feel-good chemicals that act on the same receptors as opioids. This creates a pleasurable feedback loop, making it more likely that we’ll continue drinking to chase that feeling.

The Sinclair Method (TSM)
Is Naltrexone the Ozempic for Alcohol Dependency?

Is Naltrexone the Ozempic for Alcohol Dependency?

Published on: 16/10/2024

In this blog post, we will explore the similarities and differences between naltrexone and Ozempic, delve into how they work on different receptors in the brain, and discuss innovative approaches like The Sinclair Method and Rethink Drink.

The Sinclair Method (TSM)
Insights from Recent Articles

Insights from Recent Articles

Published on: 17/09/2024

This shift is particularly evident in articles published by reputable sources such as The Telegraph and The Times, which have highlighted innovative approaches to managing alcohol use. One such approach is the Sinclair Method, a treatment that utilises Naltrexone to help individuals reduce their drinking habits.

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